Axl-IN-10

Names

[ CAS No. ]:
2487649-61-4

[ Name ]:
Axl-IN-10

Biological Activity

[Description]:

Axl-IN-10 (Example 1) is a potent AXL inhibitor, with an IC50 of 5 nM. Axl-IN-10 has excellent transmembrane properties.Axl-IN-10 exhibits excellent pharmacokinetic properties in an animal body. Axl-IN-10 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancer, or other diseases in mammals[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> TAM Receptor
Research Areas >> Inflammation/Immunology

[Target]

IC50: 5 nM (AXL)[1]


[References]

[1]. Xi Ning. Substituted heteroaryl compound, composition of same, and uses thereof. WO2020182188A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H25N7O2

[ Molecular Weight ]:
479.53

Related Compounds