Adenosine,3'-deoxy-3'-methyl-

Names

[ Name ]:
Adenosine,3'-deoxy-3'-methyl-

[Synonym ]:
3'-methyl-3'-deoxy-adenosine
5-cyanomethyl-3-cyclohexyl-3-methyl-oxazolidinium,chloride
3-Methyl-3-cyclohexyl-5-cyanmethyl-oxazolidinium chlorid

Biological Activity

[Description]:

3’-Deoxy-3’-α-C-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.81g/cm3

[ Boiling Point ]:
606.4ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₅N₅O₃

[ Molecular Weight ]:
265.27

[ Flash Point ]:
320.5ºC

[ Exact Mass ]:
265.11700

[ PSA ]:
119.31000

[ Vapour Pressure ]:
1.48E-15mmHg at 25°C

[ Index of Refraction ]:
1.818

Synthetic Route

Click to get detail synthetic route

Related Compounds

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