2′,3′-Anhydroadenosine

Names

[ CAS No. ]:
2627-64-7

[ Name ]:
2′,3′-Anhydroadenosine

[Synonym ]:
2',3'-anhydro-adenosine
9-(2,3-epoxy-β-D-ribofuranosyl)adenine
2',3'-O-anhydroadenosine
O2',O3'-Anhydro-adenosin
β-9-[2'.3'-Epoxy-D-ribofuranosido]-adenin

Biological Activity

[Description]:

2′,3′-Anhydroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C10H11N5O3

[ Molecular Weight ]:
249.23

[ Exact Mass ]:
249.08600

[ PSA ]:
111.61000

[ Vapour Pressure ]:
7.8E-15mmHg at 25°C

Precursor & DownStream

Precursor

DownStream