Nantenine

Names

[ Name ]:
Nantenine

[Synonym ]:
(S)-nantenine
(S)-1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-benzo[de][1,3]dioxolo[4',5':4,5]benzo[1,2-g]quinoline
Domestine
O-Methyldomesticine
Nantenin
Domesticine,O-methyl

Biological Activity

[Description]:

Nantenine is a serotonergic receptor antagonist. Nantenine selectively inhibits the contractile response of tissues to serotonin. Nantenine can be isolated from Nandina domestica[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[References]

[1]. Shoji N, et al Serotonergic Receptor Antagonist from Nandina dornestica Thunberg. J Pharm Sci. 1984 Apr;73(4):568-70.

Chemical & Physical Properties

[ Density]:
1.266g/cm3

[ Boiling Point ]:
487.5ºC at 760 mmHg

[ Melting Point ]:
113-114 °C

[ Molecular Formula ]:
C₂₀H₂₁NO₄

[ Molecular Weight ]:
339.39

[ Flash Point ]:
145.2ºC

[ Exact Mass ]:
339.14700

[ PSA ]:
40.16000

[ LogP ]:
3.12250

[ Vapour Pressure ]:
1.18E-09mmHg at 25°C

[ Index of Refraction ]:
1.615

Synthetic Route

Click to get detail synthetic route

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.