<Suppliers Price>

Tetrachloroguaiacol

Names

[ CAS No. ]:
2539-17-5

[ Name ]:
Tetrachloroguaiacol

[Synonym ]:
tetrachloropyrocatechol methyl ether
2,3,4,5-Tetrachlor-6-methoxy-phenol
Phenol, 2,3,4,5-tetrachloro-6-methoxy-
2,3,4,5-Tetrachloro-6-methoxyphenol
3.4.5.6-Tetrachlor-2-hydroxy-1-methoxy-benzol
tetrachloroguaiacol
3,4,5,6-Tetrachloroguaiacol
Tetrachlorofluorescein
2,3,4,5-tetrachloro-6-methoxy-phenol
3',4',5',6'-tetrachlorofluorescein
4,5,6,7-tetrachlorofluorescein
3',4',5',6'-Tetrachlor-fluorescein
Fluorescein,tetrachloro

Biological Activity

[Description]:

Tetrachloroguaiacol is the major chlorinated phenol produced during chlorine bleaching of wood pulp[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Tetrachloroguaiacol inhibits renal xenobiotic elimination[1].

[References]

[1]. A. O. J. Oikari, et al. Inhibition of renal xenobiotic excretion by tetrachloroguaiacol: Mechanism and possible consequences. Environ Toxicol Chem.1995 May; 14 (4): 669-677.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
316.0±37.0 °C at 760 mmHg

[ Melting Point ]:
119-121 °C (lit.)

[ Molecular Formula ]:
C7H4Cl4O2

[ Molecular Weight ]:
261.918

[ Flash Point ]:
144.9±26.5 °C

[ Exact Mass ]:
259.896545

[ PSA ]:
29.46000

[ LogP ]:
4.60

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.597

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SL8100000
CHEMICAL NAME :
Phenol, 2-methoxy-3,4,5,6-tetrachloro-
CAS REGISTRY NUMBER :
2539-17-5
BEILSTEIN REFERENCE NO. :
1878535
LAST UPDATED :
199710
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C7-H4-Cl4-O2
MOLECULAR WEIGHT :
261.91
WISWESSER LINE NOTATION :
QR BG CG DG EG FO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1690 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 45,295,1978 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4004 mg/kg/26W-C
TOXIC EFFECTS :
Liver - changes in liver weight
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 8,589,1979

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.