ROCK-IN-6

Names

[ CAS No. ]:
2489328-74-5

[ Name ]:
ROCK-IN-6

Biological Activity

[Description]:

ROCK-IN-6 is a potent and selectiveROCK2 inhibitor with an IC50 of 2.19 nM. ROCK-IN-6 is extracted from patent WO2021164351 A1, example 7, has the potential for glaucoma and retinal diseases research[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> ROCK
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Stem Cell/Wnt >> ROCK
Signaling Pathways >> TGF-beta/Smad >> ROCK

[Target]

ROCK2:2.19 nM (IC50)


[References]

[1]. Shen wang et al. Nitrooxyderivative of rock kinase inhibitor. Patent WO2021164351 A1

Chemical & Physical Properties

[ Molecular Formula ]:
C19H19N5O8S

[ Molecular Weight ]:
477.45

Related Compounds