Gly-His

Names

[ Name ]:
Gly-His

[Synonym ]:
GLY-HIS
N-Glycyl-L-histidine
Gly-L-His-L-Lis-OH
L-Gly-L-His-OH
Gly-L-His-OH
gly-his free base
glycylhistidine
Gly-His-OH
(2S)-2-(glycylamino)-3-(4H-imidazol-4-yl)propionic acid
glycyl-L-histidine

Biological Activity

[Description]:

(S)-2-(2-Aminoacetamido)-3-(1H-imidazol-4-yl)propanoic acid is a histidine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.56g/cm3

[ Molecular Formula ]:
C₈H₁₂N₄O₃

[ Molecular Weight ]:
212.20600

[ Exact Mass ]:
212.09100

[ PSA ]:
121.10000

[ Vapour Pressure ]:
3.33E-18mmHg at 25°C

[ Index of Refraction ]:
1.604

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ HS Code ]:
2933290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Effect of carnosine and related compounds on the inactivation of human Cu,Zn-superoxide dismutase by modification of fructose and glycolaldehyde.

Biosci. Biotechnol. Biochem. 66 , 36-43, (2002)

Glycolaldehyde, an intermediate of the Maillard reaction, and fructose, which is mainly derived from the polyol pathway, rapidly inactivate human Cu,Zn-superoxide dismutase (SOD) at the physiological ...

Reduction of vanadium(V) to vanadium(IV) by NADPH, and vanadium(IV) to vanadium(III) by cysteine methyl ester in the presence of biologically relevant ligands.

Biochim. Biophys. Acta 1770(8) , 1212-8, (2007)

To better understand the mechanism of vanadium reduction in ascidians, we examined the reduction of vanadium(V) to vanadium(IV) by NADPH and the reduction of vanadium(IV) to vanadium(III) by L-cystein...

A comparative study of complex formation in the reactions of gold(III) with Gly-Gly, Gly-L-Ala and Gly-L-His dipeptides.

Bioorg. Chem. 38(4) , 144-8, (2010)

Proton NMR spectroscopy was applied to study the reactions of the dipeptides glycyl-glycine (Gly-Gly) and glycyl-L-alanine (Gly-L-Ala) with hydrogen tetrachloridoaurate(III) (H[AuCl(4)]). All reaction...