ERAP2-IN-1

Names

[ CAS No. ]:
2420551-38-6

[ Name ]:
ERAP2-IN-1

Biological Activity

[Description]:

ERAP2-IN-1 (compound 61) is an uncompetitive ERAP2 inhibitor. ERAP2-IN-1 specifically inhibits the ERAP2 peptide hydrolysis activity, inhibiting Arg-AMC hydrolysis with an IC50 of 27 μM and model peptide hydrolysis with an IC50 of 44 μM[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Arya R, et al. Phenylsulfamoyl Benzoic Acid Inhibitor of ERAP2 with a Novel Mode of Inhibition. ACS Chem Biol. 2022 Jun 29.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₁F₃N₂O₅S

[ Molecular Weight ]:
458.45

Related Compounds

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