Acid Ceramidase-IN-1

Names

[ Name ]:
Acid Ceramidase-IN-1

Biological Activity

[Description]:

Acid Ceramidase-IN-1 is a potent and oral bioavailable acid ceramidase (AC, ASAH-1) inhibitor (hAC IC50=0.166 μM). Acid Ceramidase-IN-1 has excellent brain penetration in mice[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Di Martino S, et al. Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors. J Med Chem. 2020;63(7):3634-3664.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₂₅N₃O₃

[ Molecular Weight ]:
331.41

Related Compounds

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