Anticancer agent 61

Names

[ Name ]:
Anticancer agent 61

Biological Activity

[Description]:

Anticancer agent 61 (compound 3v) is an orally active and potent anticancer agent. Anticancer agent 61 shows antiproliferative activity in HepG2, Bel-7402 and MCF-7 cancer cells, with IC50 values of 1.12, 1.97 and 1.08 μM, respectively. Anticancer agent 61 shows effective tumor growth inhibition[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vivo]

Anticancer agent 61 (compound 3v) (BALB/c mice, 0-100 mg/kg, IV, once daily for 14 times) substantially reduces human HepG2 xenograft mouse tumor growth by 54.5% at 50 mg/kg[1].

[References]

[1]. Liu Y, et al. Synthesis and structure-activity relationship study of water-soluble carbazole sulfonamide derivatives as new anticancer agents. Eur J Med Chem. 2020 Apr 1;191:112181.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₂N₃Na₂O₈PS

[ Molecular Weight ]:
565.44

Related Compounds

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