N-caproylglycine

Names

[ Name ]:
N-caproylglycine

[Synonym ]:
Hexanoyl Glycine
Acide (hexanoylamino)acétique
2-(hexanoylamino)acetic acid
N-Hexanoylglycine
N-hexanoyl-Glycine
N-caproylglycine
(Hexanoylamino)acetic acid
Glycine, N-(1-oxohexyl)-

Biological Activity

[Description]:

Hexanoylglycine is an endogenous metabolite present in Urine that can be used for the research of Ethylmalonic Encephalopathy[1][2].

[Related Catalog]:

Research Areas >> Neurological Disease

[In Vitro]

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].

[References]

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.

[2]. Nowaczyk MJ, et al. Ethylmalonic and methylsuccinic aciduria in ethylmalonic encephalopathy arise from abnormal isoleucine metabolism. Metabolism. 1998 Jul;47(7):836-9.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
387.2±25.0 °C at 760 mmHg

[ Melting Point ]:
90-92°C

[ Molecular Formula ]:
C₈H₁₅NO₃

[ Molecular Weight ]:
173.210

[ Flash Point ]:
188.0±23.2 °C

[ Exact Mass ]:
173.105194

[ PSA ]:
66.40000

[ LogP ]:
0.71

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.462

[ Storage condition ]:
Refrigerator

Safety Information

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%