Caproic anhydride

Names

[ CAS No. ]:
2051-49-2

[ Name ]:
Caproic anhydride

[Synonym ]:
n-Caproic anhydride
Caproic anhydride
n-hexanoic acid anhydride
n-hexanoic anhydride
MFCD00009509
caproic acid anhydride
hexanoic acid hexanoyl ester
Hexanoic acid, anhydride
Hexanoic acid,anhydride
5VOV5
EINECS 218-121-4
Hexanoic anhydride

Biological Activity

[Description]:

Hexanoic anhydride is used as a reactant for the synthesis of acremomannolipin A. For the green synthesis of acyclovir dipivoxil (acyclovir prodrug), for the preparation of hexanoyl-modified chitosan nanoparticles, chitosan-based polymer surfactants by N-acylation of chitosan .

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
247.0±0.0 °C at 760 mmHg

[ Melting Point ]:
-40 °C

[ Molecular Formula ]:
C₁₂H₂₂O₃

[ Molecular Weight ]:
214.301

[ Flash Point ]:
116.6±4.7 °C

[ Exact Mass ]:
214.156891

[ PSA ]:
43.37000

[ LogP ]:
3.77

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.436

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2915900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles

Complexation-triggerable liposome mixed with silk protein and chitosan.

J. Biomater. Sci. Polym. Ed. 26 , 766-79, (2015)

Complexation-triggerable liposomes were prepared by modifying the surface of egg phosphatidylcholine (EPC) liposomes with hydrophobicized silk fibroin (HmSF) and hydrophobicized chitosan (HmCh). Maxim...

Synthesis of chitosan-based polymeric surfactants and their adsorption properties for heavy metals and fatty acids.

Int. J. Biol. Macromol. 36(3) , 152-8, (2005)

Chitosan-based polymeric surfactants (CBPSs) were prepared by N-acylation of chitosans (chitosan 10 and 500) with several acid anhydrides such as hexanoic (C6), lauric (C12), and palmitic (C16) anhydr...

Preparation, characterization and protein loading of hexanoyl-modified chitosan nanoparticles.

Drug Deliv. 13(5) , 375-81, (2006)

Hexanoyl chitosan was synthesized through a coupling reaction between chitosan and hexanoic anhydride. Proton nuclear magnetic resonance (1HNMR) and fourier-transform infrared (FTIR) spectroscopy stud...