JNJ-67569762

Names

[ CAS No. ]:
2380313-26-6

[ Name ]:
JNJ-67569762

Biological Activity

[Description]:

JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket (IC50 = 2.7 nM).

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Beta-secretase

Research Areas >> Neurological Disease

[References]

[1]. Rombouts FJR, et al. JNJ-67569762, A 2-Aminotetrahydropyridine-Based Selective BACE1 Inhibitor Targeting the S3 Pocket: From Discovery to Clinical Candidate. J Med Chem. 2021 Oct 14;64(19):14175-14191.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₂F₄N₄O₅S

[ Molecular Weight ]:
530.49

Related Compounds

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