hCAIX-IN-3

Names

[ CAS No. ]:
2375461-31-5

[ Name ]:
hCAIX-IN-3

Biological Activity

[Description]:

hCAII-IN-3 (compound 7e) is a potent and selective inhibitor of carbonic anhydrase (CA II/IX) with Kis of 124.2 and 30.5 nM, respectively. hCAII-IN-3 has the potential for the research of cancer diseases[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase

[References]

[1]. Nocentini A, et al. Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors. Eur J Med Chem. 2020;186:111896.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H21BrN6O4S

[ Molecular Weight ]:
533.40

Related Compounds