SRI-37264

Names

[ Name ]:
SRI-37264

Biological Activity

[Description]:

SRI-37264 (SRI 37264) is a small molecule inhibitor of HIV-1 Nef-mediated activation of the myeloid Src-family kinase Hck, blocks HIV-1 replication in macrophages and disrupts MHC-I downregulation.

[References]

1. Lori A Emert-Sedlak, et al. ACS Infect Dis. 2022 Jan 14;8(1):91-105.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₄ClN₃O₃S

[ Molecular Weight ]:
375.827

Related Compounds

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