2-Thiazoline, 2-methyl-
Names
[ CAS No. ]:
2346-00-1
[ Name ]:
2-Thiazoline, 2-methyl-
[Synonym ]:
2-Methyl-4,5-dihydro-1,3-thiazole
2-Thiazoline, 2-methyl-
T5N CS AUTJ B1
2-Methyl-4,5-dihydrothiazole
2-Methyl-2-Thiazoline
4,5-Dihydro-2-methylthiazole
Thiazole,4,5-dihydro-2-methyl
2-Methylthiazoline
EINECS 219-071-6
2-THIAZOLINE,2-METHYL
4,5-dihydro-2-methyl-1,2-thiazole
Methyl-2-thiazoline
Thiazole, 4,5-dihydro-2-methyl-
MFCD00005314
2-methyl-2-thiazolines
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
145.0±0.0 °C at 760 mmHg
[ Melting Point ]:
-101.0 °C(lit.)
[ Molecular Formula ]:
C4H7NS
[ Molecular Weight ]:
101.170
[ Flash Point ]:
37.2±0.0 °C
[ Exact Mass ]:
101.029922
[ PSA ]:
37.66000
[ LogP ]:
-0.51
[ Vapour Pressure ]:
6.3±0.2 mmHg at 25°C
[ Index of Refraction ]:
1.591
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XJ4261470
- CHEMICAL NAME :
- Thiazole, 4,5-dihydro-2-methyl-
- CAS REGISTRY NUMBER :
- 2346-00-1
- BEILSTEIN REFERENCE NO. :
- 0104274
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C4-H7-N-S
- MOLECULAR WEIGHT :
- 101.18
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 480 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 24(1),55,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 24(1),55,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 20,16,1985
Safety Information
[ Symbol ]:
GHS02
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H226
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R10
[ Safety Phrases ]:
S16
[ RIDADR ]:
UN 1993 3/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
XJ4261470
[ Packaging Group ]:
III
[ Hazard Class ]:
3
[ HS Code ]:
29341000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934100090
[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
Articles
Gig. Tr. Prof. Zabol. (10) , 55-6, (1980)
[Nasal chemoreception in utero: preliminary experiences in fetal sheep].
C. R. Acad. Sci. III 313(7) , 319-25, (1991)
Intranasal injections of a fragrant solution of 2-methyl-2-thiazoline elicited significant heart rate decelerations in late pregnancy fetal sheep, while the injection of a control fluid (isotonic sali...