SRI-37330 HCl

Names

[ Name ]:
SRI-37330 HCl

Biological Activity

[Description]:

SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. SRI-37330 hydrochloride inhibits glucagon secretion and function, reduces hepatic glucose production and reverses hepatic steatosis. SRI-37330 hydrochloride can be used for type 2 diabetes research[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[Target]

TXNIP[1]

[References]

[1]. Thielen LA, et al. Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action. Cell Metab. 2020 Sep 1;32(3):353-365.e8.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₂₀ClF₃N₄O₂S

[ Molecular Weight ]:
424.87

Related Compounds

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