2322245-49-6

2322245-49-6 structure

Name: SRI-37330 HCl
Chemical Name: SRI-37330 HCl
CAS Number: 2322245-49-6
Molecular Formula: C₁₆H₂₀ClF₃N₄O₂S
Molecular Weight: 424.87
Catalog: Research Areas Metabolic Disease
Create Date: 2022-08-17 19:12:18
Modify Date: 2025-08-27 11:52:26
SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. SRI-37330 hydrochloride inhibits glucagon secretion and function, reduces hepatic glucose production and reverses hepatic steatosis. SRI-37330 hydrochloride can be used for type 2 diabetes research[1].

Name	SRI-37330 HCl

Description	SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. SRI-37330 hydrochloride inhibits glucagon secretion and function, reduces hepatic glucose production and reverses hepatic steatosis. SRI-37330 hydrochloride can be used for type 2 diabetes research[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	TXNIP[1]
References	[1]. Thielen LA, et al. Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action. Cell Metab. 2020 Sep 1;32(3):353-365.e8.

Molecular Formula	C₁₆H₂₀ClF₃N₄O₂S
Molecular Weight	424.87