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Cas9-IN-3

Names

[ CAS No. ]:
2322051-02-3

[ Name ]:
Cas9-IN-3

Biological Activity

[Description]:

Cas9-IN-3 is a potent Cas9 inhibitor (IC50=28 μM). CRISPR/Cas systems have revolutionized gene editing in various species[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Cell Cycle/DNA Damage >> CRISPR/Cas9

[Target]

IC50: 28 μM (Cas9)[1]


[References]

[1]. Lee SW, et al. Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening. J Med Chem. 2022;65(4):3266-3305.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H21NO

[ Molecular Weight ]:
279.38


Related Compounds