Benzo[h]quinoline

Names

[ CAS No. ]:
230-27-3

[ Name ]:
Benzo[h]quinoline

[Synonym ]:
7,8-Bnzoquinoline
α-Naphthoquinoline
Benzo[h]quinoline
5-AZAPHENANTHRENE
benzoquinoline
7,8-Benzoquinoline
benzo<h>quinoline
EINECS 205-937-0
7,8-Benoz(h)quinoline
MFCD00004984
4-Azaphenanthrene
BENZO(H)QUINOLINE

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
340.8±0.0 °C at 760 mmHg

[ Melting Point ]:
48-50 °C(lit.)

[ Molecular Formula ]:
C₁₃H₉N

[ Molecular Weight ]:
179.217

[ Flash Point ]:
155.9±11.9 °C

[ Exact Mass ]:
179.073502

[ PSA ]:
12.89000

[ LogP ]:
3.32

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.727

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DK1432000

CHEMICAL NAME :: Benzo(h)quinoline

CAS REGISTRY NUMBER :: 230-27-3

BEILSTEIN REFERENCE NO. :: 0120249

LAST UPDATED :: 199803

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C13-H9-N

MOLECULAR WEIGHT :: 179.23

WISWESSER LINE NOTATION :: T B666 CNJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 50 ug/plate

REFERENCE :: 50NNAZ "Polynuclear Aromatic Hydrocarbons, International Symposium, 7th, 1982," Cooke, M., and A.J. Dennis, eds., Columbus, OH, Battelle Press, 1983 Volume(issue)/page/year: 7,73,1983

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DK1432000

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis of novel benzo[h]quinolines: Wound healing, antibacterial, DNA binding and in vitro antioxidant activity

Eur. J. Med. Chem. 44 , 981-9, (2009)

We have characterized a new class of 2-mercapto/2-selenobenzo[ h]quinoline-3-carbaldehyde ( 3/ 4). Antibacterial potential of these compounds against a wide range of Gram-positive and Gram-negative ba...

Determination of basic nitrogen-containing polynuclear aromatic hydrocarbons formed during thermal degradation of polymers by high-performance liquid chromatography-fluorescence detection.

J. Chromatogr. A. 878(2) , 171-81, (2000)

A method for the simultaneous determination of 22 nitrogen-containing polynuclear aromatic hydrocarbons (PAHs) (15 azaarenes and seven amino-PAHs) in the gaseous products of the thermal degradation of...

Mutagenicity and tumorigenicity of dihydrodiols, diol epoxides, and other derivatives of benzo(f)quinoline and benzo(h)quinoline.

Cancer Res. 49(1) , 20-4, (1989)

The mutagenic activities of benzo[f]quinoline, benzo[h]quinoline, and a number of their derivatives, including dihydrodiols, K-region oxides, diol epoxides, and tetrahydroepoxides, were assessed in st...