2-Acetoxy-N,N,N-trimethylethanaminium iodide

Names

[ Name ]:
2-Acetoxy-N,N,N-trimethylethanaminium iodide

[Synonym ]:
[14C]-Acetylcholine iodide
acetylthiocholine iodide
(2-Acetoxyethyl)trimethylammonium iodide
Acetylcolina [Italian]
acetylcholin iodide
Choline,iodide,acetate (ester)
Acetylcholine iodide
EINECS 218-862-3
Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, iodide (1:1)
MFCD00011815
2-Acetoxy-N,N,N-trimethylethanaminium iodide
[2H]-Acetylcholine iodide
2-(ACETYLOXY)-N,N,N-TRIMETHYLETHANAMINIUM IODIDE
Choline,acetyl-,iodide (6CI,7CI)
Acetylcholinium iodide

Biological Activity

[Description]:

Acetylcholine iodide is a common neurotransmitter found in the central and peripheral nerve system[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. MEITES J, et al. Induction and maintenance of mammary growth and lactation in rats with acetylcholine or epinephrine. Proc Soc Exp Biol Med. 1959 Apr;100(4):750-4.

Chemical & Physical Properties

[ Melting Point ]:
161-164 °C

[ Molecular Formula ]:
C₇H₁₆INO₂

[ Molecular Weight ]:
273.112

[ Exact Mass ]:
273.022552

[ PSA ]:
26.30000

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KH3300000

CHEMICAL NAME :: Ethanamium, 2-(acetyloxy)-N,N,N-trimethyl-, iodide

CAS REGISTRY NUMBER :: 2260-50-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C7-H16-N-O2.I

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 23,887,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 155 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 21,51,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJNEAQ International Journal of Neuropharmacology. (New York, NY) V.1-8, 1962-69. For publisher information, see NEPHBW. Volume(issue)/page/year: 8,131,1969

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
KH3300000

[ HS Code ]:
2923900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2923900090

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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