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UCSF686

Names

[ CAS No. ]:
2248852-19-7

[ Name ]:
UCSF686

Biological Activity

[Description]:

UCSF686 is a probe with which to study the function of the 5-HT5AR. UCSF686 loses affinity at 5-HT5AR (>10 000 nM) but not at 5-HT1AR, 5-HT2BR, and 5-HT7R. UCSF686 controls for off-target effects[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor
Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[References]

[1]. Levit Kaplan A, et al. Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor. J Med Chem. 2022;65(5):4201-4217.

Chemical & Physical Properties

[ Molecular Formula ]:
C14H19N3O2S

[ Molecular Weight ]:
293.38

Related Compounds

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