PI3Kdelta inhibitor 1

Names

[ CAS No. ]:
2242109-74-4

[ Name ]:
PI3Kdelta inhibitor 1

Biological Activity

[Description]:

PI3Kdelta inhibitor 1 (Compound 5d) is a potent, selective and orally available PI3Kδ inhibitor with an IC50 of 1.3 nM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PI3K/Akt/mTOR >> PI3K
Research Areas >> Inflammation/Immunology

[Target]

PI3Kδ:1.3 nM (IC50)


[References]

[1]. Hamajima T, et al. Optimization and in vivo evaluation of pyrazolopyridines as a potent and selective PI3Kδ inhibitor. Bioorg Med Chem. 2018 Aug 7;26(14):3917-3924.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H38N6O5S

[ Molecular Weight ]:
558.69

Related Compounds