SHIN-2

Names

[ CAS No. ]:
2204289-53-0

[ Name ]:
SHIN-2

[Synonym ]:
SHIN-2

Biological Activity

[Description]:

(Rac)-SHIN2 is a serine hydroxymethyltransferase (SHMT) inhibitor having 1,4-dihydropyrano[2,3-c]pyrazole structure. (Rac)-SHIN2 involves in folate or one-carbon metabolism pathways, prevents viral infection. SHMT1 and SHMT2 are the cytosolic and/or mitochondrial isoforms of serine hydroxymethyltransferase, respectively[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[Target]

Serine hydroxymethyltransferase (SHMT)[1]

[References]

[1]. Mootha Vamsi, et al. Method of treating and preventing viral infection comprising inhibitors of folate or one-carbon metabolism pathways such as serine hydroxymethyltransferase inhibitors: World Intellectual Property Organization, WO2022120195[P]. 2022-06-09.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₆N₄O₃

[ Molecular Weight ]:
406.48

Related Compounds

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