BMS-986278

Names

[ CAS No. ]:
2170126-74-4

[ Name ]:
BMS-986278

Biological Activity

[Description]:

BMS-986278 is a potent lysophosphatidic acid receptor 1 (LPA1) antagonist, with a human LPA1 Kb of 6.9 nM.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> LPL Receptor

[References]

[1]. Cheng PTW, et al. Murphy BJ. Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA1) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases. J Med Chem. 2021 Nov 11;64(21):15549-15581.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₃₁N₅O₅

[ Molecular Weight ]:
445.51

[ Storage condition ]:
2-8°C

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.