SOCE inhibitor 1

Names

[ CAS No. ]:
2169316-15-6

[ Name ]:
SOCE inhibitor 1

Biological Activity

[Description]:

SOCE inhibitor 1 is a store-operated calcium entry (SOCE) inhibitor with an IC50 of 4.4 μM.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> CRAC Channel

Research Areas >> Metabolic Disease

Research Areas >> Neurological Disease

[Target]

IC50: 4.4 μM (SOCE)[1]

[References]

[1]. Riva B, et al. Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis. J Med Chem. 2018 Nov 8;61(21):9756-9783.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₂F₃N₅O₄

[ Molecular Weight ]:
513.47

Related Compounds

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