Viminol

Names

[ CAS No. ]:
21363-18-8

[ Name ]:
Viminol

[Synonym ]:
1-[1-(2-chloro-benzyl)-pyrrol-2-yl]-2-(di-sec-butyl-amino)-ethanol
Viminol
Viminol [INN]
Viminolo [DCIT]
Diviminol
EINECS 244-347-8
Viminolo [Italian]
Viminolum [INN-Latin]

Biological Activity

[Description]:

Viminol is a centrally acting analgesic agent. Viminol also shows antitussive activity[1][2].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor
Signaling Pathways >> Neuronal Signaling >> Opioid Receptor
Research Areas >> Neurological Disease

[References]

[1]. D Chiarino, et al. Stereochemistry of viminol, a novel central analgesic. Arzneimittelforschung. 1978;28(9):1554-61.  

[2]. G Sabot, et al. Controlled evaluation of the antitussive activity of viminol p-hydroxybenzoate. Int J Clin Pharmacol Biopharm. 1977 Apr;15(4):181-3.  

Chemical & Physical Properties

[ Density]:
1.07g/cm3

[ Boiling Point ]:
321.3ºC at 760mmHg

[ Molecular Formula ]:
C21H31ClN2O

[ Molecular Weight ]:
362.94

[ Flash Point ]:
148.1ºC

[ Exact Mass ]:
362.21200

[ PSA ]:
28.40000

[ LogP ]:
5.12220

[ Vapour Pressure ]:
0.000125mmHg at 25°C

[ Index of Refraction ]:
1.544

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UX9635500
CHEMICAL NAME :
Pyrrole-2-methanol, 1-(o-chlorobenzyl)-alpha-((di-sec-butylamino)methyl)-
CAS REGISTRY NUMBER :
21363-18-8
BEILSTEIN REFERENCE NO. :
0444219
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H31-Cl-N2-O
MOLECULAR WEIGHT :
362.99
WISWESSER LINE NOTATION :
T5NJ A1R BG& BYQ1NY2&1&Y2&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
325 mg/kg
TOXIC EFFECTS :
Behavioral - analgesia
REFERENCE :
BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,5,1972

Related Compounds

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