8-Chloroguanosine

Names

[ Name ]:
8-Chloroguanosine

[Synonym ]:
Guanosine,8-chloro
8-Chloroguanosine

Biological Activity

[Description]:

8-Chloroguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
2.35 g/cm3

[ Boiling Point ]:
764.7ºC at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₂ClN₅O₅

[ Molecular Weight ]:
317.69

[ Flash Point ]:
416.3ºC

[ Exact Mass ]:
317.05300

[ PSA ]:
159.51000

[ Vapour Pressure ]:
1.38E-24mmHg at 25°C

[ Index of Refraction ]:
1.956

Related Compounds

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