m-PEG2-CH2CH2COOH

Names

[ CAS No. ]:
209542-49-4

[ Name ]:
m-PEG2-CH2CH2COOH

[Synonym ]:
3-[2-(2-methoxy-ethoxy)-ethoxy]-propionic acid
m-PEG3-acid
mPEG2-CH2COOH

Biological Activity

[Description]:

m-PEG2-CH2CH2COOH is PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[References]

[1]. Benzo[b]thiophene amide derivative and use thereof. WO2018121607A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₈H₁₆O₅

[ Molecular Weight ]:
192.21000

[ Exact Mass ]:
192.10000

[ PSA ]:
64.99000

[ LogP ]:
0.14070

m-PEG2-CH2CH2COOH

Names

Biological Activity

Chemical & Physical Properties

Related Compounds