VBIT-12

Names

[ CAS No. ]:
2089227-65-4

[ Name ]:
VBIT-12

Biological Activity

[Description]:

VBIT-12 is a potent VDAC1 inhibitor. VBIT-12 directly interacts with VDAC1 and prevents VDAC1 oligomerization, and thus inhibits apoptotic action of VDAC1[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[Target]

VDAC1[1]

[In Vitro]

VBIT-12 inhibits VDAC1 oligomerization, hexokinase (HK) detachment and apoptotic cell death[1].

[References]

[1]. Shoshan-Barmatz V, et al. VDAC1, mitochondrial dysfunction, and Alzheimer's disease. Pharmacol Res. 2018 May;131:87-101.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₇N₃O₃

[ Molecular Weight ]:
417.50

Related Compounds

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