5-Bromo-2-oxindole

Names

[ CAS No. ]:
20870-78-4

[ Name ]:
5-Bromo-2-oxindole

[Synonym ]:
2H-Indol-2-one, 5-bromo-1,3-dihydro-
5-Bromo-1,3-dihydro-2H-indol-2-one
5-Bromo-1,3-dihydro-indol-2-one
5-Bromooxindole
1H-indol-5-yl hypobroMite
5-BROMO-2-OXOINDOLE
5-BROMOINDOLIN-2-ONE
5-BROMO-2-INDOLINONE
MFCD00456998
5-BROMO-2-OXYINDOLE
5-bromo-2-oxo-1,2-dihydro-indole

Biological Activity

[Description]:

5-Bromoindolin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
362.5±42.0 °C at 760 mmHg

[ Melting Point ]:
220-224 °C(lit.)

[ Molecular Formula ]:
C₈H₆BrNO

[ Molecular Weight ]:
212.04

[ Flash Point ]:
173.0±27.9 °C

[ Exact Mass ]:
210.963272

[ PSA ]:
29.10000

[ LogP ]:
2.36

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.625

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H317-H319

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36/37-S36/37/39-S22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933790090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Articles

Synthesis and biological evaluation of new pyridone-annelated isoindigos as anti-proliferative agents.

Molecules 19(9) , 13076-92, (2014)

A selected set of substituted pyridone-annelated isoindigos 3a-f has been synthesized via interaction of 5- and 6-substituted oxindoles 2a-f with 6-ethyl-1,2,9-trioxopyrrolo[3,2-f]quinoline-8-carboxyl...