F 14679

Names

[ CAS No. ]:
208109-38-0

[ Name ]:
F 14679

Biological Activity

[Description]:

F 14679 is a prototypical 5-HT1A agonist with a pKi of 10.23. F 14679 induces large Ca2+ responses[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor
Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[Target]

5-HT1A Receptor:10.23 (pKi)

5-HT1B Receptor:5.12 (pIC50)


[References]

[1]. Pauwels PJ, et al. Ca2+ responses in Chinese hamster ovary-K1 cells demonstrate an atypical pattern of ligand-induced 5-HT1A receptor activation. J Pharmacol Exp Ther. 2003 Nov;307(2):608-14.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H25ClF2N4O

[ Molecular Weight ]:
422.90

Related Compounds