TNF-α-IN-2
Names
[ CAS No. ]:
2074702-04-6
[ Name ]:
TNF-α-IN-2
Biological Activity
[Description]:
TNF-α-IN-2 is a potent and orally active of tumor necrosis factor alpha (TNFα), with an IC50 of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis.
Chemical & Physical Properties
[ Molecular Formula ]:
C25H21ClF2N6O
[ Molecular Weight ]:
494.92
Related Compounds
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