HDAC-IN-58

Names

[ CAS No. ]:
2071224-39-8

[ Name ]:
HDAC-IN-58

Biological Activity

[Description]:

HDAC-IN-58 is a HDAC inhibitor. HDAC-IN-58 has HDAC6-specific inhibition activity with an IC50 value of 2.06 nM. HDAC-IN-58 can be used for the research of chronic diseases, including neurodegenerative and psychiatric conditions[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC
Research Areas >> Neurological Disease
Signaling Pathways >> Epigenetics >> HDAC

[Target]

IC50: 2.06 nM (HDAC6)[1]


[References]

[1]. Motlová L, et al. Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6). ACS Chem Biol. 2023 Jul 21;18(7):1594-1610.  

Chemical & Physical Properties

[ Molecular Formula ]:
C16H13ClF2N4O3S

[ Molecular Weight ]:
414.81

Related Compounds