PD1-PDL1-IN 1

Names

[ CAS No. ]:
2005454-12-4

[ Name ]:
PD1-PDL1-IN 1

Biological Activity

[Description]:

PD1-PDL1-IN 1 is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1

Research Areas >> Inflammation/Immunology

[In Vitro]

PD-1 (or Programmed Cell Death 1 or PDCD1) is a ~55kD type I membrane glycoprotein and is a receptor of the CD28 superfamily that negatively regulates T cell antigen receptor signalling by interacting with the specific ligands. PD-1 is suggested to play significant role in the maintenance of self-tolerance[1].

[References]

[1]. Pottayil Govindan Nair Sasikumar , et al. 3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators. WO2016142886A2.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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