6-Methylpurine

Names

[ CAS No. ]:
2004-03-7

[ Name ]:
6-Methylpurine

[Synonym ]:
1H-purine, 6-methyl-
6-Methyl-1H-purine
6-methyl-7H-purine
1H-Purine,6-methyl
6-Methylpurine
9H-Purine, 6-methyl-
6-Methyl-9H-purine
Purine,6-methyl
EINECS 217-903-2
MFCD00012137

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
410.9±25.0 °C at 760 mmHg

[ Melting Point ]:
237-238ºC(lit.)

[ Molecular Formula ]:
C₆H₆N₄

[ Molecular Weight ]:
134.139

[ Flash Point ]:
212.7±16.1 °C

[ Exact Mass ]:
134.059250

[ PSA ]:
54.46000

[ LogP ]:
0.09

[ Appearance of Characters ]:
off-white

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.696

[ Storage condition ]:
Store at RT.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UO8700000

CHEMICAL NAME :: Purine, 6-methyl-

CAS REGISTRY NUMBER :: 2004-03-7

LAST UPDATED :: 199710

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H6-N4

MOLECULAR WEIGHT :: 134.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD10 - Lethal Dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1700 ug/kg

TOXIC EFFECTS :: Blood - changes in cell count (unspecified)

REFERENCE :: PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 7,69,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0388-0723

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H310-H317-H318

[ Precautionary Statements ]:
P262-P280-P301 + P312 + P330-P302 + P352 + P310-P305 + P351 + P338 + P310

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
T: Toxic;Xn: Harmful;

[ Risk Phrases ]:
R23/24/25;R41;R43

[ Safety Phrases ]:
26-36/37/39-45

[ RIDADR ]:
UN 2811

[ WGK Germany ]:
3

[ RTECS ]:
UO8700000

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Accumulation of 19 environmental phenolic and xenobiotic heterocyclic aromatic compounds in human adipose tissue.

Environ. Int. 78 , 45-50, (2015)

The extensive use of environmental phenols (e.g., bisphenol A) and heterocyclic aromatic compounds (e.g., benzothiazole) in consumer products as well as widespread exposure of humans to these compound...

Screening of bisphenol A, triclosan and paraben analogues as modulators of the glucocorticoid and androgen receptor activities.

Toxicol. In Vitro 29(1) , 8-15, (2014)

A homeostasis of the glucocorticoid and androgen endocrine system is essential to human health. Their disturbance can lead to various diseases, for example cardiovascular, inflammatory and autoimmune ...

Spatial distribution, temporal variation and risks of parabens and their chlorinated derivatives in urban surface water in Beijing, China.

Sci. Total Environ. 539 , 262-70, (2015)

The occurrence and distribution of 13 target compounds, including eight parabens, four chlorinated parabens and p-hydroxybenzoic acid (PHBA), were detected in surface water samples at 35 sampling site...