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ML364

Names

[ CAS No. ]:
1991986-30-1

[ Name ]:
ML364

[Synonym ]:
2-[(4-methylphenyl)sulfonylamino]-N-(4-phenyl-1,3-thiazol-2-yl)-4-(trifluoromethyl)benzamide

Biological Activity

[Description]:

ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2), and can be used for the research of breast cancer, extracted from patent WO 2016134026 A1, compound Figure 10G.

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase
Research Areas >> Cancer

[Target]

USP2[1]


[References]

[1]. Methods and materials for assessing chemotherapy responsiveness and treating cancer. WO 2016134026 A1


[Related Small Molecules]

BAY 11-7082 | P5091 | PR-619 | VLX1570 | Degrasyn(WP1130) | P 22077 | DUBs-IN-2 | NSC 687852 | GNE-6776 | ML 323 | HBX 19818 | IU1 | LDN-57444 | USP7/USP47 inhibitor

Chemical & Physical Properties

[ Molecular Formula ]:
C24H18F3N3O3S2

[ Molecular Weight ]:
517.541

[ Exact Mass ]:
517.074

[ Appearance of Characters ]:
white solid

[ Storage condition ]:
-20℃