Chamigrenol

Names

[ CAS No. ]:
19822-80-1

[ Name ]:
Chamigrenol

[Synonym ]:
Spiro[5.5]undec-2-ene-3-methanol, 7,7-dimethyl-11-methylene-
(7,7-Dimethyl-11-methylenespiro[5.5]undec-2-en-3-yl)methanol

Biological Activity

[Description]:

Chamigrenol is a Na+/K+-ATPase inhibitor with an IC50 value of 15.9 μg/mL. Chamigrenol shows strong inhibitory activities against Gram-positive and Gram-negative bacteria except Escherichia coli, with MIC values of 50 µg/mL[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Ikhoon Oh, et al. In vitro Na+/K+-ATPase inhibitory activity and antimicrobial activity of sesquiterpenes isolated from Thujopsis dolabrata. Arch Pharm Res. 2011 Dec;34(12):2141-7.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
327.7±21.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₂₄O

[ Molecular Weight ]:
220.35

[ Flash Point ]:
125.2±18.3 °C

[ Exact Mass ]:
220.182709

[ LogP ]:
5.60

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.518

Related Compounds

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