19822-80-1

19822-80-1 structure

Name: Chamigrenol
Chemical Name: (7,7-Dimethyl-11-methylenespiro[5.5]undec-2-en-3-yl)methanol
CAS Number: 19822-80-1
Molecular Formula: C₁₅H₂₄O
Molecular Weight: 220.35
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2021-09-10 11:31:54
Modify Date: 2024-01-02 17:52:08
Chamigrenol is a Na+/K+-ATPase inhibitor with an IC50 value of 15.9 μg/mL. Chamigrenol shows strong inhibitory activities against Gram-positive and Gram-negative bacteria except Escherichia coli, with MIC values of 50 µg/mL[1].

Name	(7,7-Dimethyl-11-methylenespiro[5.5]undec-2-en-3-yl)methanol
Synonyms	Spiro[5.5]undec-2-ene-3-methanol, 7,7-dimethyl-11-methylene- (7,7-Dimethyl-11-methylenespiro[5.5]undec-2-en-3-yl)methanol

Description	Chamigrenol is a Na+/K+-ATPase inhibitor with an IC50 value of 15.9 μg/mL. Chamigrenol shows strong inhibitory activities against Gram-positive and Gram-negative bacteria except Escherichia coli, with MIC values of 50 µg/mL[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Ikhoon Oh, et al. In vitro Na+/K+-ATPase inhibitory activity and antimicrobial activity of sesquiterpenes isolated from Thujopsis dolabrata. Arch Pharm Res. 2011 Dec;34(12):2141-7.