1-Chloro-2-isocyanatoethane
Names
[ CAS No. ]:
1943-83-5
[ Name ]:
1-Chloro-2-isocyanatoethane
[Synonym ]:
CHLOROETHYLISOCYANATE
1-Chloro-2-isocyanatoethane
2-chlorethylisokyanat
2-chloroethyl isothiocyanate
Isocyanic Acid 2-Chloroethyl Ester
Chlorine ethyl isocyanate
Ethane, 1-chloro-2-isocyanato-
N-2-chloroethyl isocyanate
b-Chloroethylisocyanate
MFCD00002043
2-Chloro-isocyanatoethane
β-Chloroethylisocyanate
2-chloro-ethyl isocyanate
EINECS 217-734-4
2-Chloroethyl isocya
1-chloro-2-isocyanato-ethan
CIC
1-chloro-2-isocyanato-ethane
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
135.0±0.0 °C at 760 mmHg
[ Melting Point ]:
135ºC
[ Molecular Formula ]:
C3H4ClNO
[ Molecular Weight ]:
105.523
[ Flash Point ]:
56.7±0.0 °C
[ Exact Mass ]:
104.998138
[ PSA ]:
29.43000
[ LogP ]:
1.43
[ Vapour Pressure ]:
7.9±0.2 mmHg at 25°C
[ Index of Refraction ]:
1.456
[ Storage condition ]:
2-8°C
[ Stability ]:
Stable, but moisture sensitive. Combustible. Incompatible with water, moisture, strong oxidizing agents, strong bases, acids, alcohols, amines.
[ Water Solubility ]:
reacts
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NQ8450000
- CHEMICAL NAME :
- Isocyanic acid, 2-chloroethyl ester
- CAS REGISTRY NUMBER :
- 1943-83-5
- BEILSTEIN REFERENCE NO. :
- 1071429
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C3-H4-Cl-N-O
- MOLECULAR WEIGHT :
- 105.53
- WISWESSER LINE NOTATION :
- OCN2G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 13 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 38,3379,1978
Safety Information
[ Symbol ]:
GHS02, GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H301 + H331-H315-H319-H334-H335
[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R23/24/25;R34;R42
[ Safety Phrases ]:
S26-S36-S45-S38-S36/37/39-S28A-S23
[ RIDADR ]:
UN 1993 3/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
NQ8450000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
2929109000
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2929109000
[ Summary ]:
2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
ACS Appl. Mater. Interfaces 6(10) , 7926-32, (2014)
Graphene oxide (GO) has attracted more and more attention as a promising nanomaterial in biomedical research and applications. In this study, we explore the ability of GO as nanocarrier for synthetic ...
Isocyanate binding to yeast glutathione reductase measured by fluorescence spectroscopy.Biochem. Soc. Trans. 25(1) , 47S, (1997)
Novel dynamic flow cytoenzymological determination of intracellular esterase inhibition by BCNU and related isocyanates.
Biochem. Pharmacol. 36(21) , 3731-8, (1987)
We present a novel dynamic flow cytoenzymological demonstration of the potent inhibition by the antitumour chloroethylnitrosourea BCNU of the intracellular hydrolysis of fluorescein diacetate by ester...