2-Chloroethanamine hydrochloride
Names
[ CAS No. ]:
870-24-6
[ Name ]:
2-Chloroethanamine hydrochloride
[Synonym ]:
2-Chloropropylamine HCL
β-Chloroethylamine hydrochloride
2-chloroethanamine hydrochloride
2-Chloroethylamine
2-Chloroethylazanium chloride
2-Chloroethylamine h
2-CHLOROETHYLAMINE HCL
MFCD00012887
CHLOROETHYLAMINE HYDROCHLORIDE
2-Chloroethylamine HCl anhyd.
EINECS 212-793-2
2-Chloroethylammonium chloride
1-amino-2-chloroethane hydrochloride
2-aminoethyl chloride hydrochloride
2-chloroethylamine monohydrochloride
2-Chlorethanaminhydrochlorid
2-Chloroethanamine hydrochloride (1:1)
Ethanamine, 2-chloro-, hydrochloride (1:1)
Chemical & Physical Properties
[ Density]:
1.038 g/cm3
[ Boiling Point ]:
108.9ºC at 760 mmHg
[ Melting Point ]:
140-150 °C(lit.)
[ Molecular Formula ]:
C2H7Cl2N
[ Molecular Weight ]:
115.990
[ Exact Mass ]:
114.995552
[ PSA ]:
26.02000
[ LogP ]:
1.68620
[ Index of Refraction ]:
1.427
[ Water Solubility ]:
SOLUBLE
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KR1800000
- CHEMICAL NAME :
- Ethylamine, 2-chloro-, hydrochloride
- CAS REGISTRY NUMBER :
- 870-24-6
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C2-H6-Cl-N.Cl-H
- MOLECULAR WEIGHT :
- 116.00
- WISWESSER LINE NOTATION :
- Z2G &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2204 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - rat Liver
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,11,1981
Safety Information
[ Symbol ]:
GHS05, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314-H341
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
UN3261
[ WGK Germany ]:
3
[ RTECS ]:
KR1800000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2921199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921199090
[ Summary ]:
2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Nucleic Acids Res. 21 , 5179, (1993)
The condensation of 5'-O-protected 3'-O-(2-aminoethyl)thymidine with 1,2-dideoxy-1-thyminyl-beta-D-erythro-pentofuranuronic acid gives a T*T dimer with * representing a 3'-OCH2CH2NHC(O)-4' linkage con...
In the search for new anticancer drugs. XXIV: Synthesis and anticancer activity of amino acids and dipeptides containing the 2-chloroethyl- and [N'-(2-chloroethyl)-N'-nitroso]-aminocarbonyl groups.J. Pharm. Sci. 82 , 1, (1993)
A series of L,L- (42, 44, 46, and 60) and D,D- (43, 45, 47, and 61) dipeptide derivatives composed of phenylglycine, phenylalanine, homophenylalanine, and valine and containing a 2-chloroethylamino gr...