YIR-819
Names
[ CAS No. ]:
1883372-86-8
[ Name ]:
YIR-819
Biological Activity
[Description]:
YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS.
[References]
References 1. Ohashi N, et al. ChemMedChem. 2016 Apr 19;11(8):940-6. View Related Products by Target HIV
Chemical & Physical Properties
[ Molecular Formula ]:
C23H34ClN7O3
[ Molecular Weight ]:
492.021
Related Compounds
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