L-Alanine-d4

Names

[ Name ]:
L-Alanine-d4

[Synonym ]:
2,3,3,3-tetradeuterioL-alanine
|A-Aminopropionic Acid-d4
L-Alanine-2,3,3,3-d
L-(2,3,3,3-H)Alanine
|A-Alanine-d4
L-|A-Alanine-d4
2,3,3,3-Tetradeuterio-L-alanin
L-2-Aminopropanoic Acid-d4
L-alanine-d4
L-(2,3,3,3-(2)H4)alanine
alanine-C-d4
L-Alanine-2,3,3,3-d4
Lactamine-d4
2,3,3,3-tetradeuterio-L-alanine
MFCD00084109

Biological Activity

[Description]:

L-Alanine-d4 (L-2-Aminopropionic acid-d4) is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

[Related Catalog]:

Research Areas >> Metabolic Disease

Research Areas >> Neurological Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
212.9±23.0 °C at 760 mmHg

[ Melting Point ]:
314.5ºC (dec.)(lit.)

[ Molecular Formula ]:
C₃H₃D₄NO₂

[ Molecular Weight ]:
93.118

[ Flash Point ]:
82.6±22.6 °C

[ Exact Mass ]:
93.072784

[ PSA ]:
63.32000

[ LogP ]:
-0.68

[ Vapour Pressure ]:
0.1±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.460

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Alkylation or Silylation for Analysis of Amino and Non-Amino Organic Acids by GC-MS?

Metabolites 1 , 3-20, (2014)

Gas chromatography-mass spectrometry (GC-MS) is a widely used analytical technique in metabolomics. GC provides the highest resolution of any standard chromatographic separation method, and with moder...