L-Alanine-d4

Modify Date: 2024-01-02 09:25:57

L-Alanine-d4 Structure
L-Alanine-d4 structure
Common Name L-Alanine-d4
CAS Number 18806-29-6 Molecular Weight 93.118
Density 1.2±0.1 g/cm3 Boiling Point 212.9±23.0 °C at 760 mmHg
Molecular Formula C3H3D4NO2 Melting Point 314.5ºC (dec.)(lit.)
MSDS Chinese USA Flash Point 82.6±22.6 °C

 Use of L-Alanine-d4


L-Alanine-d4 (L-2-Aminopropionic acid-d4) is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

 Names

Name (2S)-2-amino-2,3,3,3-tetradeuteriopropanoic acid
Synonym More Synonyms

 L-Alanine-d4 Biological Activity

Description L-Alanine-d4 (L-2-Aminopropionic acid-d4) is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 212.9±23.0 °C at 760 mmHg
Melting Point 314.5ºC (dec.)(lit.)
Molecular Formula C3H3D4NO2
Molecular Weight 93.118
Flash Point 82.6±22.6 °C
Exact Mass 93.072784
PSA 63.32000
LogP -0.68
Vapour Pressure 0.1±0.9 mmHg at 25°C
Index of Refraction 1.460

 Safety Information

RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~%

L-Alanine-d4 Structure

L-Alanine-d4

CAS#:18806-29-6

Literature: Journal of Biochemistry (Tokyo, Japan), , vol. 46, p. 1675

 Precursor & DownStream

Precursor  1

DownStream  0

 Articles1

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Alkylation or Silylation for Analysis of Amino and Non-Amino Organic Acids by GC-MS?

Metabolites 1 , 3-20, (2014)

Gas chromatography-mass spectrometry (GC-MS) is a widely used analytical technique in metabolomics. GC provides the highest resolution of any standard chromatographic separation method, and with moder...

 Synonyms

2,3,3,3-tetradeuterioL-alanine
|A-Aminopropionic Acid-d4
L-Alanine-2,3,3,3-d
L-(2,3,3,3-H)Alanine
|A-Alanine-d4
L-|A-Alanine-d4
2,3,3,3-Tetradeuterio-L-alanin
L-2-Aminopropanoic Acid-d4
L-alanine-d4
L-(2,3,3,3-(2)H4)alanine
alanine-C-d4
L-Alanine-2,3,3,3-d4
Lactamine-d4
2,3,3,3-tetradeuterio-L-alanine
MFCD00084109