8-Quinolinesulfonyl chloride

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
355.9±17.0 °C at 760 mmHg

[ Melting Point ]:
126-129 °C(lit.)

[ Molecular Formula ]:
C₉H₆ClNO₂S

[ Molecular Weight ]:
227.667

[ Flash Point ]:
169.0±20.9 °C

[ Exact Mass ]:
226.980774

[ PSA ]:
55.41000

[ LogP ]:
1.95

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.647

[ Storage condition ]:
2-8°C

Click to get detail MSDS

CHEMICAL IDENTIFICATION

RTECS NUMBER :

VC2830000

CHEMICAL NAME :

8-Quinolinesulfonyl chloride

CAS REGISTRY NUMBER :

18704-37-5

BEILSTEIN REFERENCE NO. :

0156347

LAST UPDATED :

199612

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
VC2830000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
29334990

Precursor

DownStream

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Carbonic anhydrase inhibitors: synthesis of water-soluble, topically effective intraocular pressure lowering aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl moieties: is the tail more important than the ring?

Bioorg. Med. Chem. 7(11) , 2397-406, (1999)

Reaction of 20 aromatic/heterocyclic sulfonamides containing a free amino, imino, hydrazino or hydroxyl group, with 8-quinoline-sulfonyl chloride afforded a series of water-soluble (as hydrochloride o...

QSAR study on carbonic anhydrase inhibitors: aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl moieties, with topical activity as antiglaucoma agents.

Eur. J. Med. Chem. 39(7) , 593-600, (2004)

Quantitative structure-activity-relationship (QSAR) study on aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl carbonic anhydrase (CA) inhibitors has been carried out topologically us...

H. Takaku et al.

J. Org. Chem. 45 , 3347, (1980)

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