8-Bromoquinoline
Names
[ CAS No. ]:
16567-18-3
[ Name ]:
8-Bromoquinoline
[Synonym ]:
Quinoline, 8-bromo-
quinolin-8-yl bromide
MFCD00191859
8-Brom-chinolin
8-BROMQUINOLINE
Quinoline,8-bromo
8-Bromoquinoline
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
303.0±0.0 °C at 760 mmHg
[ Melting Point ]:
58-59 °C
[ Molecular Formula ]:
C9H6BrN
[ Molecular Weight ]:
208.055
[ Flash Point ]:
132.8±19.8 °C
[ Exact Mass ]:
206.968353
[ PSA ]:
12.89000
[ LogP ]:
2.51
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.674
[ Storage condition ]:
Refrigerator (+4°C)
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933499090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933499090
[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Dalton Trans. 39(45) , 11081-90, (2010)
The ambiphilic molecule 8-(dimesitylboryl)quinoline (1) was synthesized by treatment of 8-bromoquinoline or 8-iodoquinoline with n-BuLi followed by dimesitylboronfluoride. Hydrolysis of 1 is unusually...
Direct synthesis of tricyclic 5H-pyrido[3,2,1-ij]quinolin-3-one by domino palladium catalyzed reaction.Org. Biomol. Chem. 4(20) , 3760-2, (2006)
Unexpectedly, the palladium catalyzed coupling reaction of acrolein with 8-bromoquinoline gave 5H-pyrido[3,2,1-ij]quinolin-3-one in a single step.
Facile synthesis of 8-substituted quinolines. Suggs JW and Pearson GDN.J. Org. Chem. 45(8) , 1514-15, (1980)