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PROTAC Linker 2

Names

[ CAS No. ]:
1835705-52-6

[ Name ]:
PROTAC Linker 2

Biological Activity

[Description]:

PROTAC Linker 2 is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand.

[Related Catalog]:

Signaling Pathways >> PROTAC >> PROTAC Linker
Research Areas >> Cancer
Research Areas >> Others

[References]

[1]. Lai AC, et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. Angew Chem Int Ed Engl. 2016 Jan 11;55(2):807-10.

[2]. ARYL SULFONOHYDRAZIDES. US 20170121321 A1.


[Related Small Molecules]

N33-TEG-COOH | Boc-C1-PEG2-C4-Cl | Cl-C6-PEG4-O-CH2COOH | Protac linker 5

Chemical & Physical Properties

[ Molecular Formula ]:
C21H41ClO4

[ Molecular Weight ]:
393

Related Compounds