C5a Anaphylatoxin (human) trifluoroacetate salt

Names

[ CAS No. ]:
1816940-05-2

[ Name ]:
C5a Anaphylatoxin (human) trifluoroacetate salt

[Synonym ]:
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[2-(3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]-1,3-dimethyl-
5-[2-(3,4-Dihydro-1(2H)-quinolinyl)-2-oxoethyl]-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione

Biological Activity

[Description]:

C5a Anaphylatoxin (human) is a pro-inflammatory peptide and a leukocyte chemoattractant. C5a Anaphylatoxin (human) can be used to study inflammation and immunity, such as allergic asthma[1][2].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Complement System
Research Areas >> Inflammation/Immunology

[References]

[1]. Monk PN, et al. Function, structure and therapeutic potential of complement C5a receptors. Br J Pharmacol. 2007 Oct;152(4):429-48.  

[2]. Köhl J, et al. A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma. J Clin Invest. 2006 Mar;116(3):783-96.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
550.4±52.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H19N3O4

[ Molecular Weight ]:
329.350

[ Flash Point ]:
260.6±23.0 °C

[ Exact Mass ]:
329.137543

[ LogP ]:
0.21

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.584

Related Compounds