α-CGRP (human) trifluoroacetate salt

Names

[ Name ]:
α-CGRP (human) trifluoroacetate salt

[Synonym ]:
Human calcitonin gene-related peptide 1
alpha-Calcitonin gene-related peptide (human)
β-CGRP (human)

Biological Activity

[Description]:

α-CGRP(human) is a regulatory neuropeptide of 37 amino acids. α-CGRP(human) is widely distributed in the central and peripheral nervous system. α-CGRP(human) is a potent vasodilator[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Ambrish Kumar, et al. Protective Role of α-Calcitonin Gene-Related Peptide in Cardiovascular Diseases. Front Physiol. 2019 Jul 2;10:821.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆₃H₂₆₇N₅₁O₄₉S₂

[ Molecular Weight ]:
3789.31

[ Storage condition ]:
-20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

Articles

STC1 interference on calcitonin family of receptors signaling during osteoblastogenesis via adenylate cyclase inhibition.

Mol. Cell. Endocrinol. 403 , 78-87, (2015)

Stanniocalcin 1 (STC1) and calcitonin gene-related peptide (CGRP) are involved in bone formation/remodeling. Here we investigate the effects of STC1 on functional heterodimer complex CALCRL/RAMP1, exp...

Increasing expression of substance P and calcitonin gene-related peptide in synovial tissue and fluid contribute to the progress of arthritis in developmental dysplasia of the hip.

Arthritis. Res. Ther. 17(1) , 4, (2015)

Developmental dysplasia of the hip (DDH) is a common musculoskeletal disorder that has pain and loss of joint function as major pathological features. In the present study, we explored the mechanisms ...

The role of TRPV1 in different subtypes of dorsal root ganglion neurons in rat chronic inflammatory nociception induced by complete Freund's adjuvant.

Mol. Pain 4 , 61, (2008)

The present study aims to investigate the role of transient receptor potential vanilloid 1 (TRPV1) in dorsal root ganglion (DRG) neurons in chronic pain including thermal hyperalgesia and mechanical a...