Azido-PEG1-NHS ester
Names
[ CAS No. ]:
1807530-06-8
[ Name ]:
Azido-PEG1-NHS ester
[Synonym ]:
1-{[3-(2-Azidoethoxy)propanoyl]oxy}-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-[3-(2-azidoethoxy)-1-oxopropoxy]-
MFCD26793773
Biological Activity
[Description]:
Azido-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Related Catalog]:
[Target]
PEGs
Alkyl/ether
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C9H12N4O5
[ Molecular Weight ]:
256.215
[ Exact Mass ]:
256.080780
[ LogP ]:
-1.51